Why are the symptoms permanent?


  • Lyme disease, also known as Lyme borreliosis, is caused by the bite of an infected tick.
  • About 50,000 cases are diagnosed by general practitioners in France each year.
  • If erythema appears in the bite area, antibiotic treatment should be followed.

In June 2018, the Haute Autorité de Santé officially recognized the existence of persistent and unexplained symptoms of Lyme disease in some patients. From these words, it refers to muscle pain, fatigue or headache. ,At the current state of knowledge, we do not know whether these signs are due to persistent Lyme borreliosis (after treatment or not) or the existence of other pathogens that would be transmitted by ticks.“, then specifies HAS. American scientists have provided an explanation. In their research, published in scientific reportGeeta Parthasarathy and Shiv Kumar Gaur Gadila point out that these persistent symptoms may be linked to remnants of the bacteria responsible for disease remaining in the body.

Persistent disorder despite treatment

Two researchers from Tulane University recall that Lyme disease is primarily caused by bacteria. Borrelia burgdorferi. It is transmitted to humans by infected ticks and causes an erythema on the skin within 3 to 30 days after the bite. Prompt antibiotic treatment can prevent the onset of the disease. ,However, approximately 10 to 35% of patients treated for erythema migrans or early Lyme disease experience persistent or intermittent musculoskeletal, cognitive, or fatigue disorders of mild to moderate intensity after 6 to 12 months of follow-up.Scientists say.

dead pieces of bacteria

Prior to this study, he had already worked on an in vitro model. This time, they used monkeys, whose cerebral cortex and dorsal root ganglia they analyzed after infection with the bacteria. In their findings, they found that non-viable pieces of bacteria produced more inflammation than live fragments. Since they are more easily distributed throughout the body, they may cause signs of inflammation to appear throughout the body. According to him, the presence of these fragments in the nervous system is a possible explanation for the persistence of symptoms. For writers, it’s needed”New anti-inflammatory approaches” for treatment.

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