A “cancer killer” virus is being tested on a patient in a clinical trial

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[EN VIDÉO] What is the difference between bacteria and virus?
They are germs. They are very small and they get confused quite easily. However, bacteria and viruses are two very different things. And in order to effectively fight against those that cause the disease, it is better to clearly identify them.

as part of a clinical trialsponsored by the company of Biotechnology Australian Imagination, a volunteer cancer metastasized and resistant to previous treatment attempts, have just been administered virus “Cancer killer”, or oncolytic to scientists. CF33-hNIS or Vaccinia is an orthopoxvirus like monkeypox, which has been modified in the laboratory to express . Ashamed human – then we talk of a virus incurable – which makes it possible to follow replica in cells and enhances its anti-cancer properties.

The latter is able to infect and kill cancer cells while sparing healthy ones. When a cancer cell dies, it releases virus particles that stimulate them immune systemSpecially T cells specialized in tumor destruction, who then attack their neighbors. , Our previous research has shown that oncolytic viruses can stimulate the immune system to kill cancer and make it more reagent For other immunotherapy , Dareng Lee, principal investigator of this clinical trial, explains,

A new approach to cancer on the test bench

Clinical trials will test the safety and tolerability of CF33-hNIS alone or in combination with therapeutic antibodies, pembrolizumab, is already authorized for the treatment of many cancers. Second, scientists will analyze the ability to reduce the size of oncolytic viruses tumor,

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Actual effectiveness of this treatment anticancer Only during the later stages of the clinical trial will the estimate be made. investigators expect to be victimized by a hundred volunteers, adults and any tumor type Solidacross the United States and Australia.

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