Hope for first messenger RNA vaccine

Messenger RNA vaccine against AIDS is in the testing phase and has just been administered to macaques: the first results are promising, revealed researchers from the American National Institute of Allergy and Infectious Diseases who carried out this research in partnership with the Moderna Laboratory. are giving. , The technology would answer 40 years of fruitless vaccine research.

The risk of contracting HIV was reduced by 79% in seven macaques that received the messenger RNA vaccine against HIV/AIDS., It was previously attributed to rats. Some side effects have been observed, such as loss of appetite, but only temporarily.

virus transmission delay

For one year, macaques received multiple doses until antibodies were not detectable by week 58, notes the study. From week 60 onwards, they were administered viruses adapted to their species (since they cannot be infected with the human version) through the rectal mucosa, he explains. Thirteen weeks later, the researchers found that only two of the macaques had not contracted it at all. the other 5 had but The disease took longer to develop than people who were infected without the vaccine: usually 8 weeks compared to 3 weeks,

There are still improvements to be made, especially because many injections are complicated to set up (…)

Read more at Topsante.com

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