Clostridoides difficile, a chain mail bacterium

This article is retrieved from Monthly Science et Avenir – La Recherche n°902, April 2022.

Microbiology. It is probably because of its coating that clostridioides difficile (formerly called “Clostridium difficile,, It’s so hard to eradicate the nightmare of nosocomial infections in the hospital. More precisely, British researchers from the University of Newcastle have actually discovered that this bacterium is covered with a practically impermeable protein mesh. An actual coat of mail that blocks antibiotic and immune system molecules from penetrating.

One in 20 patients affected by nosocomial infection

According to a national study conducted by the public health agency France in 2017 and unveiled on June 4, 2018, 5% of hospitalized patients have nosocomial infections (caught in a health establishment), that is, one in 20 patients. make contracts. This has remained constant since the last such survey in 2012, with these surveys being conducted every five years. ,It is estimated that 4,200 deaths are linked to nosocomial infections each year.”, declared Dr Bruno Coinard, head of the Department of Infectious Diseases of the public health agency France.

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